'Wheel of 4 Tune 'mode is unlocked after beating Dino Crisis 3 on Hard Difficulty.
This one is very challenging, requiring you to hit a Randomizer icon to pick up 9–15 seconds of a randomly chosen gun. When the timer expires, so does your firepower! So you have to boost around for your life trying to hit that Randomizer again.
- For this mode, Patrick Tyler has some new casual clothes.